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The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin

Authors: Irina S Abaeva, Alexander G Bulakhov, Christopher U T Hellen, Tatyana V Pestova

Journal: Genes Dev

PubMed ID: 40169231

Doi: 10.1101/gad.352389.124

Products & Services: Mutagenesis Services Proteins, Expression, Isolation and Analysis Mutagenesis Services Protein Reagents and Products

Teleost GSDMEc regulates GSDMEa-mediated pyroptos

Authors: Hang Xu, Meng Wu, Yujian Wang, Yaoming Jiao, Yuan Chen, Zihao Yuan, Li Sun

Journal: J Adv Res

PubMed ID: 40210150

Doi: doi.org/10.1016/j.jare.2025.04.007

Products & Services: Proteins, Expression, Isolation and Analysis

Developmentally endothelial locus-1 facilitates intestinal inflammation resolution by suppressing the Cmpk2-cGAS-STING pathway and promoting reparatory macrophage transition

Authors: Meihui Tao, Li Wang, Chaoyue Chen, Mengfan Tang, Yanping Wang, Jingyue Zhang, Xi Zhao, Qinyu Feng, Junfa Chen, Wei Yan, Rong Lin, Yu Fu

Journal: Journal of Advanced Research

PubMed ID: 40288675

Doi: 10.1016/j.jare.2025.04.030

Products & Services: Mammalian Expression Recombinant Proteins

Phosphorylation dependent charge block regulate the relaxation of nuclear speckle networks

Authors: Mengjun Zhang, Zhuang Gu, Yingtian Sun, Yichen Dong, Junlin Chen, Li Shu, Suibin Ma, Jierui Guo, Yuhang Liang, Qingming Qu, Ning Fang, Chuan-Qi Zhong, Yifan Ge, Zhongwen Chen, Shaohui Huang, Xin Zhang, Bo Wang

Journal: Mol Cell

PubMed ID: 40233760

Doi: 10.1016/j.molcel.2025.03.016

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibiting Chemotherapy Immune Tolerance and Reversing Tumor Microenvironment by Macrophage-Targeted Nanohybrid Systems for Enhancing Tumor Chemo-Immunotherapy

Authors: You-Teng Qin, Zhi-Yong Rao, Jia-Xin An, Shi-Man Zhang, Yu-Zhang Wang, Ting Pan, and Xian-Zheng Zhang

Journal: Advanced Functional Materials

Doi: doi.org/10.1002/adfm.202501954

Products & Services: Recombinant Proteins

Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus

Authors: Haining Li , Luyuan Shao , Zhe Liu , Qi Liu , Ye Xiang

Journal: Nat Commun

PubMed ID: 40301360

Doi: 10.1038/s41467-025-59301-4

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis

Authors: Yihui Li, Wenqiang Sun, Xinyun Jin, Huiwen Li, Xue Liu, Jingtao Bian, Xueping Zhu

Journal: Cell Death Discov

PubMed ID: 40188090

Doi: 10.1038/s41420-025-02443-7.

Products & Services: Proteins, Expression, Isolation and Analysis

Nanosized Shikonin Disrupts Tumor-cell Mismatch Repair and Synergizes with Manganese to Sensitize Squamous Carcinoma to Immunotherapy

Authors: Shan Yu, Jingyuan Li, Jie Zhang, Guozhong Zeng, Bin Zeng, Shuyuan Song, Zhentao Lao, Haolin Chen, Zhenfu Wen, Zeyu Yang, Xiang Li, Kan Li, Le Yang, Hong Liu, Lixin Liu, Guiqing Liao, Yongming Chen, Yujie Liang

Journal: ACS Nano

PubMed ID: 40190094

Doi: 10.1021/acsnano.4c17090.

Products & Services: Proteins, Expression, Isolation and Analysis

Astragalus Polysaccharides Ameliorate Diabetic Bladder Dysfunction via Normalization of Neuromuscular Conduction

Authors: Shaochan Liang, Siyuan Xu, Shenglian Ye, Lang Liang, Hongliang Li, Jiaye Liu, Yao Zhang, Feng Zou, Xiaodan Liang, Bo Tan, Hongying Cao

Journal: J Agric Food Chem

PubMed ID: 40032633

Doi: 10.1021/acs.jafc.4c11577

Products & Services: Proteins, Expression, Isolation and Analysis

Expediting Genome Synthesis of Corynebacterium glutamicum with An Artificial Chromosome Vector

Authors: Zhanhua Zhang, Peixiong Hong, Zebin Li, Baitao Li, Tai Chen, Yue Shen, Xiaofeng Yang, Yanrui Ye, Yun Wang, Zhanglin Lin