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Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Authors: Paul-Albert Koenig, Hrishikesh Das, Hejun Liu, Beate M Kümmerer, Florian N Gohr, Lea-Marie Jenster, Lisa D J Schiffelers, Yonas M Tesfamariam, Miki Uchima, Jennifer D Wuerth, Karl Gatterdam, Natalia Ruetalo, Maria H Christensen, Caroline I Fandrey, Sabine Normann, Jan M P T?dtmann, Steffen Pritzl, Leo Hanke, Jannik Boos, Meng Yuan, Xueyong Zhu, Jonathan L Schmid-Burgk, Hiroki Kato, Michael Schindler, Ian A Wilson, Matthias Geyer, Kerstin U Ludwig, B Martin H?llberg, Nicholas C Wu, Florian I Schmidt
Journal: Science
PubMed ID: 33436526
Doi: 10.1126/science.abe6230
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Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
Authors: Anthony T Tan, Martin Linster, Chee Wah Tan, Nina Le Bert, Wan Ni Chia, Kamini Kunasegaran, Yan Zhuang, Christine Y L Tham, Adeline Chia, Gavin J D Smith, Barnaby Young, Shirin Kalimuddin, Jenny G H Low, David Lye, Lin-Fa Wang, Antonio Bertoletti
Journal: Cell Rep
PubMed ID: 33516277
Doi: 10.1016/j.celrep.2021.108728
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Sweet Basil Has Distinct Synthases for Eugenol Biosynthesis in Glandular Trichomes and Roots with Different Regulatory Mechanisms
Authors: Vaishnavi Amarr Reddy, Chunhong Li, Kumar Nadimuthu, Jessica Gambino Tjhang, In-Cheol Jang, Sarojam Rajani
Journal: Int J Mol Sci
PubMed ID: 33445552
Doi: 10.3390/ijms22020681
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Light-stabilized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1
Authors: Seung Jun Park, Suk Won Choi, Gu Min Kim, Christian M?ller, Hyun-Sook Pai, Seong Wook Yang
Journal: Mol Plant
PubMed ID: 33524550
Doi: 10.1016/j.molp.2021.01.020
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Metaxins are core components of mitochondrial transport adaptor complexes
Authors: Yinsuo Zhao, Eli Song, Wenjuan Wang, Chung-Han Hsieh, Xinnan Wang, Wei Feng, Xiangming Wang, Kang Shen
Journal: Nat Commun
PubMed ID: 33397950
Doi: 10.1038/s41467-020-20346-2
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Ethacrynic acid, a loop diuretic, suppresses epithelial-mesenchymal transition of A549 lung cancer cells via blocking of NDP-induced WNT signaling
Authors: Yu L, Kim HJ, Park MK, Byun HJ, Kim EJ, Kim B, Nguyen MT, Kim JH, Kang GJ, Lee H, Kim SY, Rho SB, Lee CH
Journal: Biochemical pharmacology
PubMed ID: 33189676
Doi: 10.1016/j.bcp.2020.114339
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Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates
Authors: Calisto BM, Ripoll-Rozada J, Dowman LJ, Franck C, Agten SM, Parker BL, Veloso RC, Vale N, Gomes P, de Sanctis D, Payne RJ, Pereira PJB
Journal: Cell chemical biology
PubMed ID: 33096052
Doi: 10.1016/j.chembiol.2020.10.002
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A Dual-Antigen Enzyme-Linked Immunosorbent Assay Allows the Assessment of Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Seroprevalence in a Low-Transmission Setting
Authors: Hicks SM, Pohl K, Neeman T, McNamara HA, Parsons KM, He JS, Ali SA, Nazir S, Rowntree LC, Nguyen THO, Kedzierska K, Doolan DL, Vinuesa CG, Cook MC, Coatsworth N, Myles PS, Kurth F, Sander LE, Mann GJ, Gruen RL, George AJ, Gardiner EE, Cockburn IA, SARS-CoV-2 Testing in Elective Surgery Collaborators.
Journal: The Journal of Infectious Diseases
PubMed ID: 33009908
Doi: 10.1093/infdis/jiaa623
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Nsd2 Represses Endogenous Retrovirus MERVL in Embryonic Stem Cells
Authors: Tingting Gao, Fuquan Chen, Wenying Zhang, Xuan Zhao, Xiao Hu, Xinyi Lu
Journal: Stem Cells Int
PubMed ID: 33531910
Doi: 10.1155/2021/6663960
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stimulates dendritic cells to induce IL-33 expression via abundant ATP production
Authors: Hideo Kataoka, Taiki Mori, Takeshi Into
Journal: J Med Microbiol
PubMed ID: 33439115
Doi: 10.1099/jmm.0.001303
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