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The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif.
Authors: ChenMo,ChoiSuyong,JungOisun,WenTianmu,BaumChristina,ThapaNarendra,LambertPaul F,RapraegerAlan C,AndersonRicha
Journal: Sci Rep
PubMed ID: 31235839
Doi: 10.1038/s41598-019-45671-5
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Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies.
Authors: ShenKoning,GamerdingerMartin,ChanRebecca,GenseKarina,MartinEsther M,SachsNadine,KnightPatrick D,Schl?merRenate,CalabreseAntonio N,StewartKatie L,LeiendeckerLukas,BaghelAnkit,RadfordSheena E,FrydmanJudith,Deuerling
Journal: Mol. Cell
PubMed ID: 30982745
Doi: 10.1016/j.molcel.2019.03.012
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Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin.
Authors: YeLiang,SchnepfDaniel,BeckerJan,EbertKarolina,TanriverYakup,BernasconiValentina,GadHans Henrik,HartmannRune,LyckeNils,StaeheliP
Journal: Nat. Immunol.
PubMed ID: 30886417
Doi: 10.1038/s41590-019-0345-x
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CGRP signalling inhibits NO production through pannexin-1 channel activation in endothelial cells.
Authors: GaetePablo S,LilloMauricio A,PueblaMariela,PobleteInés,FigueroaXavi
Journal: Sci Rep
PubMed ID: 31138827
Doi: 10.1038/s41598-019-44333-w
Products & Services: Peptide Synthesis   
Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.
Authors: 罢补辞颁丑颈丑-颁丑颈别丑,颁丑别苍驳碍耻补苍驳-惭颈苍,惭补驰耻苍-尝颈,贬蝉耻奥别颈-尝耻苍,颁丑别苍驰补苍-颁丑耻,贵耻丑闯辞苍驳-尝颈苍驳,尝别别奥别颈-闯耻,颁丑补辞颁丑颈丑-颁丑补苍驳,尝别别贰尘颈苍测
Journal: Cell Death Differ
PubMed ID: 31127200
Doi: 10.1038/s41418-019-0348-z
Products & Services: Peptide Synthesis   
Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance.
Authors: LancasterJ N,ThyagarajanH M,SrinivasanJ,LiY,HuZ,EhrlichL
Journal: Nat Commun
PubMed ID: 31101805
Doi: 10.1038/s41467-019-09727-4
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Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Authors: Perez-RuizElisabeth,MinuteLuna,OtanoItziar,AlvarezMaite,OchoaMaria Carmen,BelsueVirginia,de AndreaCarlos,Rodriguez-RuizMaria Esperanza,Perez-GraciaJose Luis,Marquez-RodasIvan,LlacerCasilda,AlvarezMartina,de LuqueVanesa,MolinaCarmen,TeijeiraAlvaro,BerraondoPedro,MeleroIgn
Journal: Nature
PubMed ID: 31043740
Doi: 10.1038/s41586-019-1162-y
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Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.
Authors: BellScott,RousseauJustine,PengHuashan,AouabedZahia,PriamPierre,TherouxJean-Francois,JefriMalvin,TantiArnaud,WuHanrong,KolobovaIlaria,SilvieraHeika,Manzano-VargasKarla,EhresmannSophie,HamdanFadi F,HettigeNuwan,ZhangXin,AntonyanLilit,NassifChristina,Ghaloul-GonzalezLina,SebastianJessica,VockleyJerry,BegtrupAmber G,WentzensenIngrid M,CrunkAmy,NichollsRobert D,HermanKristin C,DeignanJoshua L,Al-HertaniWalla,EfthymiouStephanie,SalpietroVincenzo,MiyakeNoriko,MakitaYoshio,MatsumotoNaomichi,?sternRune,HougeGunnar,Hafstr?mMaria,FassiEmily,HouldenHenry,Klein Wassink-RuiterJolien S,NelsonDominic,GoldsteinAmy,DabirTabib,van GilsJulien,BourgeronThomas,DelormeRichard,CooperGregory M,MartinezJose E,FinnilaCandice R,CarmantLionel,LortieAnne,OegemaRenske,van GassenKoen,MehtaSarju G,HuhleDagmar,Abou JamraRami,MartinSonja,BrunnerHan G,LindhoutDick,AuMargaret,GrahamJohn M,CoubesChristine,TureckiGustavo,GravelSimon,MechawarNaguib,RossignolElsa,MichaudJacques L,LessardJulie,ErnstCarl,CampeauPhilip
Journal: Am J Hum Genet
PubMed ID: 31031012
Doi: 10.1016/j.ajhg.2019.03.022
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MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.
Authors: MeixiongJames,VasavdaChirag,SnyderSolomon H,DongXinz
Journal: Proc. Natl. Acad. Sci. U.S.A.
PubMed ID: 31068464
Doi: 10.1073/pnas.1903316116
Products & Services: Peptide Synthesis   
Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation.
Authors: 闯颈补厂丑补苍驳,贬别顿补苍,颁丑补苍驳颁丑谤颈蝉迟辞辫丑
Journal: J. Am. Chem. Soc.
PubMed ID: 31017395
Doi: 10.1021/jacs.8b11912
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