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Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex

Authors: Luke F Pennington, Pascal Gasser, Silke Kleinboelting, Chensong Zhang, Georgios Skiniotis, Alexander Eggel, Theodore S Jardetzky

Journal: Nat Commun

PubMed ID: 34862384

Doi: 10.1038/s41467-021-27397-z

Products & Services: Proteins, Expression, Isolation and Analysis

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

Authors: Emma L Lewis, Rong Xu, Jean-Christophe Beltra, Shin Foong Ngiow, Jordana Cohen, Rahul Telange, Alexander Crane, Deirdre Sawinski, E John Wherry, Paige M Porrett

Journal: J Exp Med

PubMed ID: 34882194

Doi: 10.1084/jem.20201599

Products & Services: Proteins, Expression, Isolation and Analysis

Development and validation of novel kit for quantification of SARS-CoV-2 antibodies on clinical samples

Authors: Sneha Kumari, Anoushka Raina, Dinesh Chandra, Nikita Gupta, Nikki Dey, Amit Kumar Bhardwaj, Archana Anthwal, Vikash C Mishra, Vimarsh Raina, Aseem K Tiwari, Rasika Setia, A S Bhatia

Journal: J Virol Methods

PubMed ID: 34919976

Doi: 10.1016/j.jviromet.2021.114423

Products & Services: Protein Reagents and Products

Lactobacillus lactis and Pediococcus pentosaceus-driven reprogramming of gut microbiome and metabolome ameliorates the progression of non-alcoholic fatty liver disease

Authors: Jeong Seok Yu, Gi Soo Youn, Jieun Choi, Chang-Ho Kim, Byung Yong Kim, Seung-Jo Yang, Je Hee Lee, Tae-Sik Park, Byoung Kook Kim, Yeon Bee Kim, Seong Woon Roh, Byeong Hyun Min, Hee Jin Park, Sang Jun Yoon, Na Young Lee, Ye Rin Choi, Hyeong Seob Kim, Haripriya Gupta, Hotaik Sung, Sang Hak Han, Ki Tae Suk, Do Yup Lee

Journal: Clin Transl Med

PubMed ID: 34965016

Doi: 10.1002/ctm2.634

Products & Services: Protein Reagents and Products

Engineering CAR-T cells to activate small-molecule drugs in situ

Authors: Thomas J Gardner, J Peter Lee, Christopher M Bourne, Dinali Wijewarnasuriya, Nihar Kinarivala, Keifer G Kurtz, Broderick C Corless, Megan M Dacek, Aaron Y Chang, George Mo, Kha M Nguyen, Renier J Brentjens, Derek S Tan, David A Scheinberg

Journal: Nat Chem Biol

PubMed ID: 34969970

Doi: 10.1038/s41589-021-00932-1

Products & Services: Proteins, Expression, Isolation and Analysis

Enzymatic deamination of the epigenetic nucleoside N6-methyladenosine regulates gene expression

Authors: Zhuoran Jiang, Chao Wang, Zixin Wu, Kun Chen, Wei Yang, Hexiang Deng, Heng Song, Xiang Zhou

Journal: Nucleic Acids Res

PubMed ID: 34850126

Doi: 10.1093/nar/gkab1124

Products & Services: Proteins, Expression, Isolation and Analysis

Cryptic splicing events result in unexpected protein products from calpain-10 (CAPN10) cDNA

Authors: Yasuko Ono, Naoko Doi, Mayumi Shindo, Pablo Pánico, Ana María Salazar