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LPS-induced murine systemic inflammation is driven by parenchymal cell activation and exclusively predicted by early MCP-1 plasma levels.
Authors: Juskewitch Justin E，Knudsen Bruce E，Platt Jeffrey L，Nath Karl A，Knutson Keith L，Brunn Gregory J，Grande Jose
Journal: Am. J. Pathol.
PubMed ID: 22067909
Doi: 10.1016/j.ajpath.2011.10.001
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A drug discovery platform: a simplified immunoassay for analyzing HIV protease activity.
Authors: Kitidee Kuntida，Nangola Sawitree，Hadpech Sudarat，Laopajon Witida，Kasinrerk Watchara，Tayapiwatana Chat
Journal: J. Virol. Methods
PubMed ID: 22846787
Doi: 10.1016/j.jviromet.2012.07.022
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Ligand binding assays in the 21st century laboratory: recommendations for characterization and supply of critical reagents.
Authors: O'HaraDenise M，TheobaldValerie，EganAdrienne Clements，UsanskyJoel，KrishnaMurli，TerWeeJulie，MaiaMauricio，SpriggsFrank P，KenneyJohn，SafaviAfshin，KeefeJean
Journal: AAPS J
PubMed ID: 22415613
Doi: 10.1208/s12248-012-9334-9
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Chemical reactivity and skin sensitization potential for benzaldehydes: can Schiff base formation explain everything?
Authors: 狈补迟蝉肠丑础苍诲谤别补蝉，骋蹿别濒濒别谤贬补苍蝉，贬补耻辫迟罢颈苍补，叠谤耻苍苍别谤骋别谤
Journal: Chem. Res. Toxicol.
PubMed ID: 22950880
Doi: 10.1021/tx300278t
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Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet.
Authors: DevarajanAsokan，GrijalvaVictor R，BourquardNoam，MeriwetherDavid，ImaizumiSatoshi，ShinBo-Chul，DevaskarSherin U，ReddySriniva
Journal: Mol. Genet. Metab.
PubMed ID: 22864055
Doi: 10.1016/j.ymgme.2012.06.020
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Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.
Authors: Habegger K M，Penque B A，Sealls W，Tackett L，Bell L N，Blue E K，Gallagher P J，Sturek M，Alloosh M A，Steinberg H O，Considine R V，Elmendorf
Journal: Diabetologia
PubMed ID: 22002007
Doi: 10.1007/s00125-011-2334-y
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Decreased expression of neuronal nitric oxide synthase in the nucleus tractus solitarii inhibits sympathetically mediated baroreflex responses in rat.
Authors: Lin Li-Hsien，Nitschke Dragon Deidre，Jin Jingwen，Tian Xin，Chu Yi，Sigmund Curt，Talman Willi
Journal: J. Physiol. (Lond.)
PubMed ID: 22687614
Doi: 10.1113/jphysiol.2012.237966
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Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.
Authors: Xiao Q, Ford AL, Xu J, Yan P, Lee KY, Gonzales E, West T, Holtzman DM, Lee JM.
Journal: J Neurosci
PubMed ID: 23015448
Doi: 10.1523/JNEUROSCI.2617-12.2012
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Insulin-like peptide 3 stimulates testosterone secretion in mouse Leydig cells via cAMP pathway.
Authors: PathiranaIndunil N，KawateNoritoshi，BüllesbachErika E，TakahashiMasahiro，HatoyaShingo，InabaToshio，TamadaHirom
Journal: Regul. Pept.
PubMed ID: 22800961
Doi: 10.1016/j.regpep.2012.07.003
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The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM-and DNA-PKCs-mediated DNA damage responses.
Authors: Mukherjee B, Tomimatsu N, Amancherla K, Camacho CV, Pichamoorthy N, Burma S.
Journal: Neoplasia.
PubMed ID: 22355272
Doi: 10.1593/neo.111512
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