| ￥1200 | |
| A03847-50 | |
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| Specificity | This product is specific to GABA B receptor 1 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human GABA B receptor 1 |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Target Background | Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2.Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins.Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. |
| Synonyms | GABA-B receptor 1; GABA-B-R1; GABAB R1; GABAB subunit 1c; GABABR1; GABBR1 3; Gamma aminobutyric acid (GABA) B receptor 1; Gb1; GPRC3A; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
