9I果冻制作厂官网

目录产物 » DNAM-1/CD226, His, Human
DNAM-1/CD226, His, Human

DNAM-1/CD226, His, Human

FACS analysis of DNAM-1/CD226, His, Human (Cat. No: Z03455) and CHO-K1/aAPC/CD155 Clone (CHO-K1 cell overexpressing human CD155), compared with blank control (green line, untreated cell) and negative control (blue line, only treated with THE? His Tag Antibody [iFluor 488], mAb, Mouse (Cat. No. A01800)), DNAM-1/CD226, His, Human can bind with CHO-K1/aAPC/CD155 Clone.

DNAM-1/CD226, His, Human

CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, 'platelet and T cell activation antigen 1')[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding.
Z03455
￥320

联系我们
产物介绍
Species Human
Protein Construction
DNAM-1/CD226 (Glu19-Asn247)
Accession # Q15762		 Poly-His
N-term C-term
Purity > 90% as analyzed by SDS-PAGE
Endotoxin Level < 1 EU/μg of protein by gel clotting method
Biological Activity DNAM-1/CD226, His, Human can bind with CHO-K1/aAPC/CD155 Clone by FACS analysis.
Expression System HEK 293
Apparent Molecular Weight ~39.3 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

图例
  • DNAM-1/CD226, His, Human
    • DNAM-1/CD226, His, Human

  • DNAM-1/CD226, His, Human
    • DNAM-1/CD226, His, Human

    FACS analysis of DNAM-1/CD226, His, Human (Cat. No: Z03455) and CHO-K1/aAPC/CD155 Clone (CHO-K1 cell overexpressing human CD155), compared with blank control (green line, untreated cell) and negative control (blue line, only treated with THE? His Tag Antibody [iFluor 488], mAb, Mouse (Cat. No. A01800)), DNAM-1/CD226, His, Human can bind with CHO-K1/aAPC/CD155 Clone.


技术背景
Target Background CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, 'platelet and T cell activation antigen 1')[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding.
Synonyms DNAM-1; DNAM1; PTA1; TLiSA1; CD226 molecule

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


喜欢新升级的网站吗？

讨厌

不喜欢

一般

喜欢

非常喜欢

*
Skip