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IL-17D, Human

IL-17D is a secreted cytokine with homology to the IL-17 family of proteins. It is preferentially expressed in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas. It has been reported that IL-17D has the ability to stimulate the production of other cytokines from target tissues such as endothelial cells, treatment of endothelial cells with purified rIL-17D protein stimulated the production of IL-6, IL-8, and GM-CSF. In addition, rIL-17D also demonstrated an inhibitory effect on hemopoiesis of myeloid progenitor cells in colony formation assays.
￥2800
Z03541-100

产物介绍
Species Human
Protein Construction
IL-17D (Ala18-Pro202)
Accession # Q8TAD2
Purity > 90% as analyzed by SDS-PAGE
Endotoxin Level < 1 EU/μg of protein by gel clotting method
Expression System CHO
Apparent Molecular Weight ~12.1 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background IL-17D is a secreted cytokine with homology to the IL-17 family of proteins. It is preferentially expressed in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas. It has been reported that IL-17D has the ability to stimulate the production of other cytokines from target tissues such as endothelial cells, treatment of endothelial cells with purified rIL-17D protein stimulated the production of IL-6, IL-8, and GM-CSF. In addition, rIL-17D also demonstrated an inhibitory effect on hemopoiesis of myeloid progenitor cells in colony formation assays.
Synonyms Interleukin-17D; IL-17D; IL17D
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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.