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目录产物 » Nectin-3/CD113[Biotin], His & Avi, Human
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Nectin-3/CD113[Biotin], His & Avi, Human

The Nectin family has at least four members (Nectin-1?4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein.
￥5800
Z04565-100

产物介绍
Species Human
Protein Construction
Nectin-3/CD113 (Gly58-Asp400)
Accession # Q9NQS3-1		 His Avi
N-term C-term
Conjugate Biotin
Purity >?95%?as?determined?by?Bis?Tris?PAGE
> 95%?as?determined?by?HPLC
Endotoxin Level Less than 0.05EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Nectin-3/CD113[Biotin], His & Avi, Human at 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml) can bind Human Nectin?1, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 40.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 68-82 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 20mM PB, 250mM NaCl (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background The Nectin family has at least four members (Nectin-1?4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein.
Synonyms CD113; CDw113; FLJ90624; PPR3; PVRL3; PVRR3; PRR3
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.