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目录产物 » MMP-9, His, Cynomolgus
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MMP-9, His, Cynomolgus

Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14.
¥3500
Z04875-100

Species Cynomolgus
Protein Construction
MMP-9 (Ala20-Asp706)
Accession # A0A2K5UU71
His
N-term C-term
Purity >?95%?as?determined?by?Bis?Tris?PAGE?
> 95%?as?determined?by?HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized MMP-9, His, Cynomolgus at 0.5μg/ml (100μl/Well) on the plate can bind Anti?MMP?9 Antibody, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 77.44 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 85-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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Target Background Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14.
Synonyms MMP-9; GELB; CLG4B; MANDP2; Gelatinase B
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.