| ￥3000 | |
| Z05162-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by Bis-Tris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized CEACAM-3/CD66d, His, Human at 1μg/ml (100μl/well) on the plate can bind Human CEACAM?7, hFc Tag. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 14.19 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 17-27 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Immobilized CEACAM-3/CD66d, His, Human, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.0 ng/ml determined by ELISA. ?
CEACAM-3/CD66d, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. ?
| Target Background | The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac. |
| Synonyms | CEACAM3; CD66d; CGM1; CEA; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
