Species | Human | ||||
Protein Construction |
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Purity |
> 95%?as?determined?by?Bis?Tris?PAGE? > 95%?as?determined?by?HPLC |
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Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
Expression System | HEK293 | ||||
Theoretical Molecular Weight | 38.91 kDa | ||||
Apparent Molecular Weight | Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result. | ||||
Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
The purity of GIPR hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. ?
GIPR hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. ?
Target Background | The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity. |
Synonyms | GIP-R; GIPR; PGQTL2 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.