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目录产物 » M-CSF/CSF-1, His & Avi, Human
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M-CSF/CSF-1, His & Avi, Human

CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.
￥4900
Z05640-100

产物介绍
Species Human
Protein Construction
M-CSF/CSF-1 (Glu33-Asn190)_x000D_
Accession # P09603-1		 His Avi
N-term C-term
Purity >?95%?as?determined?by?Bis?Tris?PAGE?
>?95%?as?determined?by?HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized M-CSF/CSF-1, His & Avi, Human at 0.5μg/ml (100μl/well) on the plate can bind Human M?CSF R, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 21.3 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 28-34 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.
Synonyms CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.