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目录产物 » Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer, His, Mouse

Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer, His, Mouse

Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM?1/CD54, ICAM?2, ICAM3 and JAM?1[2].
¥4100
Z06223-100

Species Mouse
Protein Construction
Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer[Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail]
Accession # P24063-1(ITGAL)&P11835(ITGB2)
His
N-term C-term
Purity >?95%?as?determined?by?Bis?Tris?PAGE?
> 95%?as?determined?by?HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2)
Apparent Molecular Weight Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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Integrin Alpha L Beta 2 (ITGAL&ITGB2) Heterodimer, His, Mouse

The purity of Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer, His, Mouse is greater than 95% as determined by SEC-HPLC. ?

Integrin Alpha L Beta 2 (ITGAL&ITGB2) Heterodimer, His, Mouse

Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. ?

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Target Background Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM?1/CD54, ICAM?2, ICAM3 and JAM?1[2].
Synonyms αLβ2; ITGAL&ITGB2; ITGAL; ITGB2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.