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Notch 4, His, Mouse

The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells.
¥3000
Z06287-100

Species Mouse
Protein Construction
Notch 4 (Glu1042-Leu1441)_x000D_
Accession # P31695
His
N-term C-term
Purity >?95%?as?determined?by?Bis?Tris?PAGE?
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 42.91 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22μm filtered solution in PB, 500mM NaCl, 10% Glycerol (pH 7.0).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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Target Background The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells.
Synonyms Notch4; Int-3; Int3; Notch-4;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.