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The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism
Authors: Jennifer A Buffa, Kymberleigh A Romano, Matthew F Copeland, David B Cody, Weifei Zhu, Rachel Galvez, Xiaoming Fu, Kathryn Ward, Marc Ferrell, Hong J Dai, Sarah Skye, Ping Hu, Lin Li, Mirjana Parlov, Amy McMillan, Xingtao Wei, Ina Nemet, Robert A Koeth, Xinmin S Li, Zeneng Wang, Naseer Sangwan, Adeline M Hajjar, Mohammed Dwidar, Taylor L Weeks, Nathalie Bergeron, Ronald M Krauss, W H Wilson Tang, Federico E Rey, Joseph A DiDonato, Valentin Gogonea, G Frank Gerberick, Jose Carlos Garcia-Garcia, Stanley L Hazen
Journal: Nat Microbiol
PubMed ID: 34949826
Doi: 10.1038/s41564-021-01010-x
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T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Authors: Muhammad Ali, Eirini Giannakopoulou, Yingqian Li, Madeleine Lehander, Stina Virding Culleton, Weiwen Yang, Cathrine Knetter, Mete Can Odabasi, Ravi Chand Bollineni, Xinbo Yang, Zsofia Foldvari, Maxi-Lu B?schen, Eli Taraldsrud, Erlend Str?nen, Mireille Toebes, Amy Hillen, Stefania Mazzi, Arnoud H de Ru, George M C Janssen, Arne Kolstad, Geir Erland Tj?nnfjord, Benedicte A Lie, Marieke Griffioen, S?ren Lehmann, Liv Toril Osnes, Jochen Buechner, K Christopher Garcia, Ton N Schumacher, Peter A van Veelen, Matthias Leisegang, Sten Eirik W Jacobsen, Petter Woll, Johanna Olweus
Journal: Nat Biotechno.
PubMed ID: 34873326
Doi: 10.1038/s41587-021-01089-x
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Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells
Authors: Alissa D Guarnaccia, April M Weissmiller, William P Tansey
Journal: STAR Protoc
PubMed ID: 34917979
Doi: 10.1016/j.xpro.2021.101000
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Generation and utility of a single-chain fragment variable monoclonal antibody platform against a baculovirus expressed recombinant receptor binding domain of SARS-CoV-2 spike protein
Authors: Reda Salem, Alaa A El-Kholy, Fatma R Waly, Dalia Ayman, Aya Sakr, Mai Hussein
Journal: Mol Immunol
PubMed ID: 34915268
Doi: 10.1016/j.molimm.2021.12.006
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Deep mutational scanning for therapeutic antibody engineering
Authors: Kyrin R Hanning, Mason Minot, Annmaree K Warrender, William Kelton, Sai T Reddy
Journal: Trends Pharmacol Sci
PubMed ID: 34895944
Doi: 10.1016/j.tips.2021.11.010
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Novel sequential immunocapture microflow LC/MS/MS approach to measuring PTH-Fc protein in human serum
Authors: Haixing Wang, Jiang Wu, Peng Pan, Thuy Nguyen, Michael Cwik, Ling Morgan
Journal: Bioanalysis
PubMed ID: 34894717
Doi: 10.4155/bio-2021-0233
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Developing a secretory AcGFP1-based IRES expression system for efficient production of mammalian recombinant proteins
Authors: Zhongcheng Zou, Matthew Spencer, Peter D Sun
Journal: Protein Expr Purif
PubMed ID: 34920134
Doi: 10.1016/j.pep.2021.106029
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Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2
Authors: Yannick Galipeau, Vinayakumar Siragam, Geneviève Laroche, Erika Marion, Matthew Greig, Michaeline McGuinty, Ronald A Booth, Yves Durocher, Miroslava Cuperlovic-Culf, Steffany A L Bennett, Angela M Crawley, Patrick M Giguère, Curtis Cooper, Marc-André Langlois
Journal: EBioMedicine
PubMed ID: 34861490
Doi: 10.1016/j.ebiom.2021.103700
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The Marine Neurotoxin Brevetoxin (PbTx-2) Inhibits and Mammalian Thioredoxin Reductases by Targeting Different Residues
Authors: Ricardo Colon, Michelle Wheater, Emily J Joyce, Emma J Ste Marie, Robert J Hondal, Kathleen S Rein
Journal: J Nat Prod
PubMed ID: 34752085
Doi: 10.1021/acs.jnatprod.1c00795
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Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs
Authors: Sophie M-C Gobeil, Benjamin G Bobay, Praveen R Juvvadi, D Christopher Cole, Joseph Heitman, William J Steinbach, Ronald A Venters, Leonard D Spicer
Journal: MBio
PubMed ID: 34809463
Doi: 10.1128/mBio.03000-21
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