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Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy

Authors: Menglong Xu, Gaoxin Lei, Manman Chen, Ke Wang, Wenxiu Lv, Panpan Zhang, Tuo Hu, Jie Gao, Chenchen Lu, Ying Mei, Zhipan Xu, Zhengli Bai, Huajing Hu, Yiwei Jiang, Shuhua Tan

Journal: EBioMedicine

PubMed ID: 33647772

Doi: 10.1016/j.ebiom.2021.103250

Products & Services: Recombinant Proteins

Genetically modified attenuated salmonid alphavirus: A potential strategy for immunization of Atlantic salmon

Authors: Ida Aksnes, Stine Braaen, Turhan Markussen, Caroline Piercey ?kesson, Stephane Villoing, Espen Rimstad

Journal: J Fish Dis

PubMed ID: 33591590

Doi: 10.1111/jfd.13352

Products & Services: Protein Tools

Protein 4 1R negatively regulates P815 cells proliferation by inhibiting C-Kit-mediated signal transduction

Authors: Ding C,Guo Y,Liang T,Liu J,Yang L,Wang T,Liu X,Kang Q

Journal: Experimental cell research

PubMed ID: 33271128

Doi: 10.1016/j.yexcr.2020.112403

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia

Authors: Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R

Journal: Pain

PubMed ID: 33009246

Doi: 10.1097/j.pain.0000000000002097

Products & Services: Proteins, Expression, Isolation and Analysis

Activin A Promotes Regulatory T-cell-Mediated Immunosuppression in Irradiated Breast Cancer

Authors: De Martino M,Daviaud C,Diamond JM,Kraynak J,Alard A,Formenti SC,Miller LD,Demaria S,Vanpouille-Box C

Journal: Cancer immunology research

PubMed ID: 33093219

Doi: 10.1158/2326-6066.CIR-19-0305

Products & Services: Recombinant Proteins

A growth-factor-activated lysosomal K channel regulates Parkinson's pathology

Authors: Jinhong Wie, Zhenjiang Liu, Haikun Song, Thomas F Tropea, Lu Yang, Huanhuan Wang, Yuling Liang, Chunlei Cang, Kimberly Aranda, Joey Lohmann, Jing Yang, Boxun Lu, Alice S Chen-Plotkin, Kelvin C Luk, Dejian Ren

Journal: Nature

PubMed ID: 33505021

Doi: 10.1038/s41586-021-03185-z

Products & Services: Proteins, Expression, Isolation and Analysis

Highly Sensitive and Specific Multiplex Antibody Assays To Quantify Immunoglobulins M, A, and G against SARS-CoV-2 Antigens

Authors: Carlota Doba?o, Marta Vidal, Rebeca Santano, Alfons Jiménez, Jordi Chi, Diana Barrios, Gemma Ruiz-Olalla, Natalia Rodrigo Melero, Carlo Carolis, Daniel Parras, Pau Serra, Paula Martínez de Aguirre, Francisco Carmona-Torre, Gabriel Reina, Pere Santamaria, Alfredo Mayor, Alberto L García-Basteiro, Luis Izquierdo, Ruth Aguilar, Gemma Moncunill

Journal: J Clin Microbiol

PubMed ID: 33127841

Doi: 10.1128/JCM.01731-20

Products & Services: Proteins, Expression, Isolation and Analysis

hsa-miR-191-5p inhibits replication of human immunodeficiency virus type 1 by downregulating the expression of NUP50

Authors: Yanghao Zheng, Zongxing Yang, Changzhong Jin, Chaoyu Chen, Nanping Wu

Journal: Arch Virol

PubMed ID: 33420627

Doi: 10.1007/s00705-020-04899-7

Products & Services: Proteins, Expression, Isolation and Analysis

Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function.

Authors: Johnston CL,Marzano NR,Paudel BP,Wright G,Benesch JLP,van Oijen AM,Ecroyd H