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Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets.

Authors: Ching Kathryn H，Collarini Ellen J，Abdiche Yasmina N，Bedinger Daniel，Pedersen Darlene，Izquierdo Shelley，Harriman Rian，Zhu Lei，Etches Robert J，van de Lavoir Marie-Cecile，Harriman William D，Leighton Phil

Journal: MAbs

PubMed ID: 29035625

Doi: 10.1080/19420862.2017.1386825

Products & Services: Proteins, Expression, Isolation and Analysis

TRPC5 Does Not Cause or Aggravate Glomerular Disease.

Authors: Wang Xuexiang，Dande Ranadheer R，Yu Hao，Samelko Beata，Miller Rachel E，Altintas Mehmet M，Reiser Jo

Journal: J. Am. Soc. Nephrol.

PubMed ID: 29061651

Doi: 10.1681/ASN.2017060682

Products & Services: Recombinant Proteins

Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization.

Authors: Jiang Mei，Liu Xinghui，Zhang Denghai，Wang Ying，Hu Xiaoxia，Xu Fengxia，Jin Mingming，Cao Fanfan，Xu L

Journal: J Neuroinflammation

PubMed ID: 29540209

Doi: 10.1186/s12974-018-1124-6

Products & Services: Recombinant Proteins

Brain Shuttle Antibody for Alzheimer's Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode.

Authors: Weber Felix，Bohrmann Bernd，Niewoehner Jens，Fischer Jens A A，Rueger Petra，Tiefenthaler Georg，Moelleken Joerg，Bujotzek Alexander，Brady Kevin，Singer Thomas，Ebeling Martin，Iglesias Antonio，Freskg?rd Per

Journal: Cell Rep

PubMed ID: 29298417

Doi: 10.1016/j.celrep.2017.12.019

Products & Services: Recombinant Proteins

Sbp1 modulates the translation of Pab1 mRNA in a poly(A)- and RGG-dependent manner.

Authors: Brandariz-Nú?ez Alberto，Zeng Fuxing，Lam Quan Ngoc，Jin

Journal: RNA

PubMed ID: 28986506

Doi: 10.1261/rna.062547.117

Products & Services: Proteins, Expression, Isolation and Analysis

MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI).

Authors: Bellón-Echeverría Itxaso，Carralot Jean-Philippe，Del Rosario Andrea Araujo，Kueng Stephanie，Mauser Harald，Schmid Georg，Thoma Ralf，Berger

Journal: Sci Rep

PubMed ID: 29572554

Doi: 10.1038/s41598-018-23516-x

Products & Services: Recombinant Proteins

Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2 Breast Cancer Metastasis to the Brain.

Authors: Priceman Saul J，Tilakawardane Dileshni，Jeang Brook，Aguilar Brenda，Murad John P，Park Anthony K，Chang Wen-Chung，Ostberg Julie R，Neman Josh，Jandial Rahul，Portnow Jana，Forman Stephen J，Brown Christi

Journal: Clin. Cancer Res.

PubMed ID: 29061641

Doi: 10.1158/1078-0432.CCR-17-2041

Products & Services: Recombinant Proteins

Cobl-like promotes actin filament formation and dendritic branching using only a single WH2 domain.

Authors: Izadi Maryam，Schlobinski Dirk，Lahr Maria，Schwintzer Lukas，Qualmann Britta，Kessels Micha

Journal: J. Cell Biol.

PubMed ID: 29233863

Doi: 10.1083/jcb.201704071

Products & Services: Proteins, Expression, Isolation and Analysis

An engineered RNA binding protein with improved splicing regulation.

Authors: Hale Melissa A，Richardson Jared I，Day Ryan C，McConnell Ona L，Arboleda Juan，Wang Eric T，Berglund J An