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Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

Authors: Matthias Schmidt, Namil Lee, Chunjun Zhan, Jacob B Roberts, Alberto A Nava, Leah S Keiser, Aaron A Vilchez, Yan Chen, Christopher J Petzold, Robert W Haushalter, Lars M Blank, Jay D Keasling

Journal: ACS Synth Biol

PubMed ID: 37851920

Doi: 10.1021/acssynbio.3c00367

Products & Services: Proteins, Expression, Isolation and Analysis

Cornelia de Lange Syndrome mutations in SMC1A cause cohesion defects in yeast

Authors: Jingrong Chen, Erin N Floyd, Dean S Dawson, Susannah Rankin

Journal: Genetics

PubMed ID: 37650609

Doi: 10.1093/genetics/iyad159

Products & Services: Proteins, Expression, Isolation and Analysis

Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2

Authors: Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

Journal: PLoS Pathog

PubMed ID: 37856551

Doi: 10.1371/journal.ppat.1011728

Products & Services: Proteins, Expression, Isolation and Analysis

Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection

Authors: Krystyna Cwiklinski, Amanda McEvoy, Jesús López Corrales, Heather Jewhurst, Nichola Eliza Davies Calvani, Carolina De Marco Verissimo, Amber Louise Dorey, Orla M Keane, John Pius Dalton, Richard Lalor

Journal: Vet Parasitol

PubMed ID: 37826973

Doi: 10.1016/j.vetpar.2023.110049

Products & Services: Proteins, Expression, Isolation and Analysis

Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models

Authors: Moyu Dai, Ning Yang, Kai Xu, Jingwen Zhang, Xueke Li, Ying Zhang, Wei Li

Journal: Cell Prolif

PubMed ID: 37864397

Doi: 10.1111/cpr.13565

Products & Services: Proteins, Expression, Isolation and Analysis

T cells Use Focal Adhesions to Pull Themselves Through Confined Environments

Authors: Alexia Caillier, David Oleksyn, Deborah J Fowell, Jim Miller, Patrick W Oakes

Journal: biorxiv

PubMed ID: 37904911

Doi: 10.1101/2023.10.16.562587

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis

Authors: Yanli Zheng, Hongmei Fu, Jue Chen, Jie Li, Yuejie Bian, Ping Hu, Lei Lei, Yihan Liu, Jiangke Yang, Wenfang Peng

Journal: Microb Cell Fact

PubMed ID: 37833755

Doi: 10.1186/s12934-023-02217-9

Products & Services: Proteins, Expression, Isolation and Analysis

MpADC, an L-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis

Authors: Pengfu Liu, Saixue Xie, Qian Guo, Yan Chen, Junying Fan, Ashok Kumar Nadda, Xiaoluo Huang, Xiaohe Chu

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 37876019

Doi: 10.1186/s13068-023-02405-0

Products & Services: Proteins, Expression, Isolation and Analysis

Author Correction: Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

Authors: Xiuyuan Ou, Ge Xu, Pei Li, Yan Liu, Fuwen Zan, Pan Liu, Jiaxin Hu, Xing Lu, Siwen Dong, Yao Zhou, Zhixia Mu, Zhiqiang Wu, Jianwei Wang, Qi Jin, Pinghuang Liu, Jian Lu, Xiangxi Wang, Zhaohui Qian

Journal: Cell Discov

PubMed ID: 37813850

Doi: 10.1038/s41421-023-00597-1

Products & Services: Proteins, Expression, Isolation and Analysis

G-quadruplexes of KSHV oriLyt play important roles in promoting lytic DNA replication

Authors: Prerna Dabral, Timsy Uppal, Subhash C Verma

Journal: Microbiol Spectr

PubMed ID: 37800915

Doi: 10.1128/spectrum.05316-22

Products & Services: Proteins, Expression, Isolation and Analysis