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hypocretin-1/hypocretin receptor 1 regulates neuroplasticity and cognitive function through hippocampal lactate homeostasis in depressed model

Authors: Bing Chen , Kangyu Jin , Jingyi Dong , Shangping Cheng , Lingzhuo Kong , Shaohua Hu , Zuobing Chen, Jing Lu

Journal: Advanced Science

PubMed ID: 39119889

Doi: 10.1002/advs.202405354

Products & Services: Proteins, Expression, Isolation and Analysis eBlot ? L1 Fast Wet Transfer System

A low-molecular-weight α-glucan from edible fungus Agaricus blazei Murrill activates macrophage TFEB-mediated antibacterial defense to combat implant-associated infection

Authors: Qishan Wang , Yuehong Wang , Yihao Liu , Kai Yuan , Yixuan Lin , Xian Qian , Hongyan Pei , Liangliang Weng , Kaijian Fan , Yihe Hu , Yiqi Yang

Journal: Carbohydrate Polymers

Doi: 10.1016/j.carbpol.2024.122659

Products & Services: Proteins, Expression, Isolation and Analysis

Rupatadine-inhibited OTUD3 promotes DLBCL progression and immune evasion through deubiquitinating MYL12A and PD-L1

Authors: Ying Sui , Ziyang Shen, Xiaoyou Li 1, Ya Lu , SiTong Feng , Rong Ma, Jianzhong Wu , Changwen Jing, Zhuo Wang, Jifeng Feng , Haixia Cao

Journal: Cell death & disease

PubMed ID: 39097608

Doi: 10.038/s41419-024-06941-x

Products & Services: Proteins, Expression, Isolation and Analysis

CLASP-mediated competitive binding in protein condensates directs microtubule growth

Authors: Xuanyan Jia , Leishu Lin, Siqi Guo , Lulu Zhou , Gaowei Jin , Jiayuan Dong , Jinman Xiao , Xingqiao Xie , Yiming Li , Sicong He , Zhiyi Wei , Cong Yu

Journal: Nature Communications

PubMed ID: 39095354

Doi: 10.1038/s41467-024-50863-3

Products & Services: Proteins, Expression, Isolation and Analysis

A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection

Authors: Xuanxiu Ren # 1, Jiawen Sun # 2 3, Wenhua Kuang # 2, Feiyang Yu 1, Bingjie Wang 1, Yong Wang 2 3, Wei Deng 2 3, Zhao Xu 2 3, Shangyu Yang 1, Hualin Wang 2 4, Yangbo Hu 2 4, Zengqin Deng 5 6, Yun-Jia Ning 7 8, Haiyan Zhao

Journal: Nature Communications

PubMed ID: 39147753

Doi: 10.1038/s41467-024-51108-z

Products & Services: Proteins, Expression, Isolation and Analysis

Reversible control of kinase signaling through chemical-induced dephosphorylation

Authors: Ying Sun , Rihong Zhou , Jin Hu , Shan Feng , Qi Hu

Journal: Communications Biology

PubMed ID: 39217250

Doi: 10.1038/s42003-024-06771-9

Products & Services: Proteins, Expression, Isolation and Analysis Recombinant Proteins

Fluorinated Titanium Oxide (TiO2-xFx) Nanospindles as Ultrasound-Triggered Pyroptosis Inducers to Boost Sonodynamic Immunotherapy

Authors: Shumin Sun , Xuan Huang , Nailin Yang , Huali Lei , Zifan Pei , Zhihui Han , Lin Liu , Fei Gong , Qiao Yu , Jingrui Li , Youdong Chen , Liang Cheng

Journal: ACS Nano

PubMed ID: 39010657

Doi: 10.1021/acsnano.4c05448

Products & Services: Proteins, Expression, Isolation and Analysis

Fit-for-purpose heterodivalent single-domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile

Authors: Everardo R Rodriguez Rodriguez, Rune Thorbj?rn Nordvang, Marcus Petersson, Jakob Kr?mmer Haar Rendsvig, Emma Wenzel Arendrup, Monica L Fernández Quintero, Timothy P Jenkins, Andreas H Laustsen, Sandra Wingaard Thrane

Journal: Protein Sci

PubMed ID: 38923049

Doi: 10.1002/pro.5035

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanism of ceramide synthase inhibition by fumonisin B1

Authors: Zike Zhang 1 2 4, Qi Fang 1 2 4, Tian Xie 1 2, Xin Gong

Journal: Structure

Doi: 10.1016/j.str.2024.06.002

Products & Services: Proteins, Expression, Isolation and Analysis

Acceptors stability modulates the efficiency of post-translational protein N-glycosylation

Authors: Paula M Couto, Carlos M A Guardia, Facundo L Couto, Carlos A Labriola, María S Labanda, Julio J Caramelo

Journal: FASEB J